you consider applying to our #OpenScience prize competition, here is a chance to ask all the questions you might have...

Our recent review delves into recent advancements involving E3 ligases and addresses the technical challenges of developing effective PROTACs. Can these emerging degraders compete with established degrader systems?
Find out🔽 sciencedirect.com/science/articl…

Preliminary results for CACHE #4 are out: 1688 compounds predicted by 23 participants to bind the TKB domain of CBLB were tested. 10 bind CBLB and not an unrelated target. 9 participants advance to Round 2: hit expansion. bit.ly/3vOCFKB Structural Genomics Consortium (SGC) Conscience

As always, great work and trenchant insights from our partners at the Structural Genomics Consortium (SGC).

'Big data and benchmarking initiatives to bridge the gap from AlphaFold to drug design

nature.com/articles/s4158…

#CADD #DrugDiscovery #OpenScience #ArtificialIntelligence

Avril est le #MoisDeLaMaladieDeParkinson .

#SVAM : Un premier concours de science ouverte organisé par Conscience a mené à une découverte prometteuse qui pourrait se traduire par de meilleurs traitements contre la #MaladieDeParkinson .

En savoir plus: conscience.ca/fr/news/consci…

April is #Parkinsons AwarenessMonth .

#ICYMI : Conscience’ first open science competition yielded a promising discovery that could lead to better treatments for #Parkinsons Disease.

Learn more: conscience.ca/news/cache-cha…

Did you miss the inaugural CACHE symposium in Toronto? The complete slide decks are now available online at Zenodo by Conscience.
🔗 Explore the presentations: zenodo.org/communities/ca…
#CACHESymposium #openscience #drugdiscovery

📢 Agora Open Science Trust is looking for a Vice President, Drug Discovery and Development. This is a great opportunity to work on a first-of-its-kind #openscience drug development initiative targeting pediatric brain cancer.
Apply: linkedin.com/jobs/view/3864…
#jobopportunity #drugdiscovery

New preprint with a promising strategy to reduce the amount of HTT protein levels to treat #huntingtonsdisease . The #SGCTeam led by Takis Prinos and Rachel Harding investigated the effects of PRMT5 inhibition on the splicing of the HTT mRNA.
biorxiv.org/content/10.110….

We attended the first CACHE Symposium, organized by Conscience and we have a lot to say! The symposium showcased the power of #openscience and #collaboration in advancing #drugdiscovery , highlighting outcomes from the first CACHE Challenge.
Read more: thesgc.org/node/1649761

📢 👏 Cheryl Arrowsmith, Matthieu Schapira and Dalia Barsyte have been awarded more than $3 million from CIHR.
Read more: bit.ly/3P5KZfj
#CancerResearch #DrugDiscovery #ChemicalProbes , #AI

New non-profit, Conscience, targeting under-researched diseases: mcgillnews.mcgill.ca/new-non-profit… McGill Faculty of Law | Faculté de droit McGill University aled edwards

🌎💜 Today is #RareDiseaseDay - a day for coming together to raise awareness of all rare conditions. At SGC our mission extends beyond the lab. We are committed to empowering scientists worldwide with tools and knowledge to explore challenging and rare diseases.