Megan Radyk, PhD
@radykm
GI biologist studying metabolism in premalignant cells. Postdoc @UMichMedicine with @LyssiotisLab & @YatrikShahLab (she/her)
ID:1071769878254706688
https://medicine.umich.edu/dept/molecular-integrative-physiology/megan-radyk-phd 09-12-2018 14:13:46
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Beyond excited to share my first paper from my PhD Daniel Fazakerley Lab Inst Metabolic Science-Metabolic Research Labs now out in The EMBO Journal! Special thanks to Sam from TVPLab and Dougall Norris for co-leading this project with me. We found that many cell culture models, despite living in 18% oxygen, are hypoxic! 🧵below:…
Somatic Mutations in Normal Tissues: Calm before the Storm
By Humam Kadara Paul Scheet 🌮🧬 Zahraa Rahal MD Anderson Cancer Center
aacrjournals.org/cancerdiscover…
What are the hallmarks of Precancer?
See our commentary in Cancer Discovery from the NCI Division of Cancer Biology TBEL Consortium (tbelprogram.org/index.html) driven by an exceptional cache of trainees & early career investigators.
aacrjournals.org/cancerdiscover…
Ken Lau Lab Lyssiotis Lab Jimin Min
Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer biorxiv.org/cgi/content/sh… #biorxiv_cancer
Cancer Biology students and Lyssiotis lab friends volunteering at the One Day Closer Day Event and teaching high school students about careers in cancer research and our facilities! 🧪🔬🧬🌟 U-M Rogel Cancer Center Michigan Medicine Lyssiotis Lab
I am happy to share that our work hots off the press today at Nature Communications where we reveal a non-canonical function of quiescence in expanding cell fate plasticity. A short thread (1/9)
nature.com/articles/s4146…
Incredible piece of work from Meritxell Rovira Jennifer Bailey Lundberg and colleagues - this resource will be widely used. A functional map of the ENTIRE normal ductal epithelium from centroacinar cells to main duct, identifying both the transcriptomic heterogeneity to organoid forming…
Commemorating the first, annual Seth Boyer Award for Excellence in Research, in memory of Seth, a UMPhysiology student in the lab. Seth was an extremely bright, hard-working, thoughtful, diligent scientist. He never backed down from a challenge and made important contributions…
Looking forward to another day of science at #KSTumorMetab24 🔬
I could get used to this view 🏔️☀️
Hear more about our discoveries in precancer metabolism later today in Workshop 2 starting at 2:30
Keystone Symposia
Colleagues Michigan Medicine, U-M Rogel Cancer Center: consider volunteering for this fun event sharing cancer science with our communities!
❤️Megan Radyk, PhD in the highlight
What are the hallmarks of stem cell metabolism? In our new review in Cell Stem Cell, Benjamin Jackson Memorial Sloan Kettering Cancer Center explains why there aren't any metabolic hallmarks; rather, metabolic networks are customized to support many different functions in stem cells sciencedirect.com/science/articl…
Happy to share a new paper from my lab just out today in Gastroenterology. The topic is about metabolic changes essential for precancerous cell lineage progression led by Yoonkyung Won! Yoonkyung Won Gastroenterology VUMC Research EBC_Vanderbilt