Check out our review on 'SGLT2i and GU infections' in JACC Journals

🔗: shorturl.at/gsGL7

Here we discuss
- SGLT2i mechanisms/benefits
- Trial/real-world evidence of SGLT2i/GU ifx
- Risk factors
- Practice considerations

🧵 to follow (1/5)

Greetings All. As many of you have likely seen, I am on the ballot this year to become a Regent of ACCP. The voting closes this Friday before Midnight Central time. I humbly ask for your support and vote. ACCP Cardiology PRN ACCP Txp PRN UConn Pharmacy

In #DICTATE trial, dapagliflozin was safe to start first day of AHF hospitalization before stabilization to optimize #GDMT & improve some measures of diuresis. #SGLT2i should be started immediately or continued in most pts hospitalized for AHF bit.ly/3VK4fmK #JACC Zachary Cox

Despite #dapagliflozin not improving diuretic efficiency in the setting of acute HF hospitalization, it was associated with fewer diuretic doses to achieve the same weight change as usual care American College of Cardiology Zachary Cox #Cardiotwitter Lipscomb College of Pharmacy

Read more👇
healio.com/news/cardiolog…

Happy #WorldDownSyndromeDay
My son Cooper brightens our day. Hope you have a friend with Down Syndrome in your life to enrich your days too.

What timing! The full paper of our evaluation of the PHARM-HF clinic is now live JACCP accpjournals.onlinelibrary.wiley.com/doi/epdf/10.10…

Read our #PUSHAHF trial here in Nature Medicine !!!

nature.com/articles/s4159…

DICTATE-AHF top line results were presented at #ESCCongress2023 KEY MESSAGE: Dapagliflozin is safe to start on the first day of AHF hospitalization to optimize #gdmt Addironally, diuretic benefits have meaningful impact on AHF discharge rates over the study period

DICTATE-AHF & PUSH-AF trials presented at #ESCCongress shed light on treatments for acute #HeartFailure ; trials assess safety/efficacy of dapagliflozin w/in 24-hour of hospitalization & use of a natriuresis-guided diuretic approach to managing pts. bit.ly/45nbCTc

DICTATE-AHF trial shows early initiation of SGLT2i dapagliflozin within 24hr of acute HF presentation does not improve diuretic efficiency, but length of stay significantly reduced with dapagliflozin. Dr. Cox and I discuss results of DICTATE-AHF #ESCCongress

Early initiation of the sodium glucose co-transporter 2 ( #SGLT2 ) inhibitor dapagliflozin did not result in a statistically significant improvement in diuretic efficiency relative to structured usual care in hospitalised patients with acute decompensated heart failure (ADHF).…

Excited to present the #DICTATE -AHF results European Society of Cardiology #ESCCongress2023 later today. HOTLINE 8 is going to be a great session full of important clinical trial results

TODAY is the LAST DAY to snag early bird registration rates 💸 for HFSA #HFSA2023 !

Check out the Advance Program: hfsa.org/sites/default/…

And register here: hfsa.org/asm/registrati…

Akshay Desai Prateeti Khazanie Zachary Cox Laura Peters, DNP, FNP-C Mitchell Psotka Jo Ellen Rodgers John R Teerlink, MD

In #COAPT , #HeartFailure specialists optimized #GDMT & documented med/dose intolerances prior to enrollment. 38.8%, 39.4% & 19.8% of pts tolerated 3, 2, & 1 GDMT classes. BB were best tolerated (93.1%) followed by ACEI/ARB/ARNI (68.5%) &MRA (55.0%) bit.ly/3pAxF9q #JACCHF

I am excited to present the late breaking results of the DICTATE-AHF trial in HOTLINE session 8 at #ESCCongress in Amsterdam.
Will be a great session along with Jozine ter Maaten presenting PUSH-AHF.
VUMC Heart/Vascular Lipscomb College of Pharmacy Lipscomb University

Very sad to hear of Timothy Keller (1950-2023) death today. He has been an unknowing mentor to me. His podcast Gospel in Life and scholarship will continue to inspire and inform me after his death. See you soon, Dr. Keller