#OnePathBoardPointAtATime
📘4 types of Rosettes/Pseudorosettes to remember:

1⃣ Homer Wright Rosette:
First described in Neuroblastoma.
Also in Medulloblastoma & other PNETs.
Tumor cells surrounding central area that contains neuropil (aka fibrillary or neuroblastic rosettes).

Duane Dibbley Horace Goodwill, tonicke purveyor 🇵🇸 Pancreatic neuroendocrine tumors (also called pNETs or islet cell tumors)

my.clevelandclinic.org/health/disease…

This week our FREE virtual education series is on PNETs and other solid lesions.

Make sure you join Dr Brian Stedman (Southampton) this Thursday 5th Oct at 1300!

You can register 👉 bit.ly/3Q9KWAp

Cases are 👉 bit.ly/3mKeiZA

#radiology #GIeducation

Does necrosis predict outcome in pancreatic neuroendocrine tumors (PNETs)?

Can it be integrated with Ki67 and mitotic count to improve the grading of these tumours?

If you want to find out - Our group's latest article available for free for 50 days at:
authors.elsevier.com/c/1fXCp77Wlj5h0

Von Hippel-lindau Syndrome (VHL) With Multiple Renal Cell Carcinomas and Multiple Pancreatic Neuroendocrine Tumors (pnets): ctisus.com/responsive/tea…

Angel Mendoza Cállese pñets 😂

INSM-1 expression correlates with the grade of Pancreatic neuroendocrine tumors (PNETs)... an excellent presentation by our PGY-2 resident Dr. David Kim. #ecc2019Malmö #cornellpathology #wcmcpathology

New #HPB video added to our atlas just in time for the AHPBA: ExVivo #Whipple & small bowel autotransplantation for #PNETs . WATCH NOW: pie.med.utoronto.ca/TVASurg/projec…
Dr. Ian McGilvray will also be presenting this video at the masters video session at the AHPBA. Don't miss it! #MedEd

2/2✳️ Prognosis is variable
✳️The 5 year survival rate is 30%for non functioning PNETs and up to 97% for functionable resectable PNETs
✳️ 2years later FNA of recurrence in liver and pancreas showed PNET remained low grade with no evidence of transformation to high grade

Main first line trials in first line pNETs. Patient’s selection remains essential. ⁦Grupo_GGNET⁩ ⁦SOGAMN gallega de nuclear⁩ ⁦Nieves Martinez Lago MD PhD⁩ ⁦Grupo GETNE⁩

This week two of my patients with stage III PNETs consented to ⁦SWOG Cancer Research Network⁩ 2104 which completely changed the conversation. We are not used to discussing adjuvant therapy for #neuroendocrine tumors and this trial is changing that. ⁦Heloisa Soares MD⁩ ⁦Syed A. Ahmad⁩

One of our favorite faculty Patricio Polanco moderating “Controversies in the Management of PNETs” at Society of Surgical Oncology

#SSO2022

CYSTIC PANCREATIC WELL-DIFFERENTIATED NEUROENDOCRINE TUMOR
kudos to Markie
▶️9-20% of PNETs are cystic
▶️ Body/tail > pancreatic head
▶️More favorable clinicopathologic features-single, non-functional, lower Ki-67, lower lymph node mets
▶️ Commonly mistaken for MCN

Sporadic non-functioning PNETS an 🇮🇹 multicentre analysis

✖️Pan NECs no surgical benefit
✖️Small G1 sporadic Pan-NENs no surgery needed
🔪Surgery alone not enough for G3 Pan NEN (💉!)

Multimodal approach necessary!

Link
academic.oup.com/bjs/advance-ar…

Those pesky PNETs, rare in real life, pandemic in the #FRCS MCQ exam. Let’s do this! The Dukes' Club TeachMeSurgery ASiT TUGSS #TUGS

⁦Richard Schulick, MD⁩ says review PNETs at a multidisciplinary tumor board because one size does not fit all! ⁦IHPBA⁩ ⁦Ana Gleisner (she/her/hers)⁩ ⁦Marco Del Chiaro⁩ ⁦Callisia Clarke MD⁩ ⁦CU Department of Surgery⁩ ⁦CU Cancer Center⁩ ⁦CU Surgical Oncology⁩

Practice changing presentation from the fabulous Pamela Kunz, MD, FASCO at #ASCO2022 GI oral session. Cape/Tem beats Tem in PNETs. MGMT+ patients having higher ORR to the combo. Congrats to the team!!! ECOG-ACRIN Cancer Research Group

Pancreatic neuroendocrine tumors ( #PNETs ) are a group of cancers that can occur in the hormone-producing cells of the pancreas and are very rare. Learn more about #neuroendocrinetumor care at Mayo Clinic: mayocl.in/2X63Mei.

Another heavy hitting #SAGES2022 HPB talk on PNETs! Nicolò Pecorelli Susanne Warner Alexandra Gangi, MD Callisia Clarke MD Thor Halfdanarson Erin Gilbert

👏👏👏What a great initiative! I love Vinay Prasad MD MPH's lecture on PFS using PNETs.

Here is an excellent article on metastatic liver NETs, which understandably doesn't mention SBRT:
link.springer.com/article/10.124…

Fortunately, #radonc continues to focus on QoL and OS - not PFS! 😉