Harvard Med Cell Bio
@HarvardCellBio
Department of Cell Biology at Harvard Medical School - dedicated to unraveling how the machines of the cell work.
ID:875322144300961792
http://cellbio.med.harvard.edu 15-06-2017 12:00:36
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New work on the kinetics of protein turnover - this was one of the last projects from our own Fred Goldberg! Thanks to the Knowles lab KnowlesLab Cambridge and Galen Collins making this a reality.
pnas.org/doi/10.1073/pn…
Cool paper from our neighbors Johannes Walter and Ernst Schmid in Harvard Med BCMP describes a new classifier for improving alphafold-based interaction screening. biorxiv.org/content/10.110…
Molecular machines rule! Frank Adolf & Jiale Du in Brenda Schulman lab Max Planck Institute of Biochemistry (MPIB) , John Hanna (BWH/Harvard), & Ellen Goodall Wade Harper Harvard Med Cell Bio visualize chaperone-mediated stepwise assembly of the 20S proteasome by cryo-EM Aligning Science Across Parkinson’s nature.com/articles/s4159…
So happy for our own Harvard Med Cell Bio faculty member David Pellman on being awarded the Clowes Award for Outstanding Basic Cancer Research by the AACR. His work on chromosome instability has been transformational!
New work from the Liberles Lab Harvard Med Cell Bio reveal a role for Piezo2 expressed in lung epithelial cells of the neuroepithelial body in a neuronal reflex of the vagus nerve evoked by airway closure that leads to gasping. nature.com/articles/s4158…
CONGRATULATIONS!! to Harvard Med Cell Bio faculty member David Pellman for receiving the AACR-G.H.A. Clowes Award for Outstanding Basic Cancer Research. So well deserved!! aacr.org/about-the-aacr…
ER remodelling by ER-phagy in neurogenesis | Nature Cell Biology. Amazing work by Melissa Hoyer Florian Wilfling The Wilfling Lab Wade Harper Harvard Med Cell Bio nature.com/articles/s4155…
ER remodeling during neurogenesis by autophagy & visualization of ER cargo capture in axons by cryo-ET Melissa Hoyer Wade Harper Harvard Med Cell Bio Cristina Capitanio Anna Bieber Brenda Schulman lab Max Planck Institute of Biochemistry (MPIB) & Florian Wilfling Max Planck Institute of Biophysics Aligning Science Across Parkinson’s
nature.com/articles/s4155…
It is with great sadness that we announce the passing of our colleague & friend Professor Dan Goodenough (Takeda Professor of Cell Biology emeritus, Harvard Med Cell Bio ), a pioneer in the study of gap junctions, an acclaimed educator & activist for change. ascb.org/member-news/in…
New work from Ann Hochschild Harvard Micro and Wade Harper & Joao Paulo Harvard Med Cell Bio develop 'translational tiling proteomics' as an unbiased way to identify non-programmed translational frameshifting by bacterial ribosomes in cells and in vitro. pnas.org/doi/10.1073/pn…
Ever wonder how molecular machines are made? Now Frank Adolf & Jiale Du in Brenda Schulman lab Max Planck Institute of Biochemistry (MPIB) , John Hanna (BWH/Harvard), & Wade Harper Harvard Med Cell Bio use cryo-EM to visualize chaperone-mediated stepwise assembly of the 20S proteasome biorxiv.org/content/10.110…
Congratulations to Harvard Med Cell Bio faculty member Ed Chouchani Ed Chouchani on receiving a Marks Foundation Emerging Leader Award! So well deserved.
Another super cool paper from Harvard Med Cell Bio faculty member Susan Shao describes a small molecule degrader for a translational termination factor!
New exciting work from Harvard Med Cell Bio faculty Kirchhausen lab identified endosomal perforations as a key feature in creation of synuclein aggregates in neurons. biorxiv.org/content/10.110…
New work from Harvard Med Cell Bio faculty Adrian Salic defines new extracellular carriers of lipid modified WNTs and the underlying mechanism transfer to FZD receptors!!
New work from Rapoport Lab Harvard Med Cell Bio identifies a new class of highly curved vesicles containing REEP1 class of reticulon homology domain proteins biorxiv.org/content/10.110…
Harvard Med Cell Bio American Society for Cell Biology #cellbio2023 Alex Panov in the Wade Harper will discuss links between protein misfolding and proteasomal degradation via the UBE3C ubiquitin ligase.
Harvard Med Cell Bio American Society for Cell Biology #cellbio2023 Arda Mizrak in the Farese & Walther Lab SKI_CellBio and Wade Harper will discuss single molecule tracking of proteins in the ER and their delivery to lipid droplets.
