Jonathan Pruneda
@jnpruneda
Assistant Professor at Oregon Health & Science University studying microbial interference in host ubiquitin signaling. Formerly @UWBiochemistry and @MRC_LMB.
ID:988372871646011392
http://www.ohsu.edu/mmi/pruneda 23-04-2018 11:03:50
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🚨Excited to share that our manuscript is now published in NatureStructMolBiol. Using #cryoEM 🔬we obtained multiple snapshots 📷 of the #chaperone -mediated multistep assembly pathway of the human 20S #proteasome .
Max Planck Institute of Biochemistry (MPIB) Harvard Med Cell Bio Aligning Science Across Parkinson’s
nature.com/articles/s4159…
Beyond excited to share our story on CUL9- a giant cullin-RING AND RBR E3 ligase. We uncovered its hexameric structure via #CryoEM and got surprised by NEDD8 along the way!
Amazing collab with LinusHopf Max Planck Institute of Biochemistry (MPIB)
Check out the full story NatureStructMolBiol nature.com/articles/s4159…
Looking for an exciting lab to do your postdoc and receive support to do your best science?! 🧪
Come have fun in Austin Molecular Biosciences while trying to solve the molecular mechanisms of (micro)biological conflicts! utaustin.wd1.myworkdayjobs.com/UTstaff/job/AU……
Please RT!
At long last, we have finally identified a degradation regulator of a specific, pupylated, proteasome substrate! An opus led by student Shoshanna Kahne in collaboration with Aravind group rheelab BhabhaEkiertLab Alejandro Pironti James Chen
Curious about E2s' role in serine and threonine ubiquitylation?🤔 Check out the latest paper from De Cesare lab MRC PPU on Science Advances! Congratulations to Arif Syed Arif Abdul Rehman
and our collaborators! #Ubiquitin #ScienceAdvancesResearch 🎉
Excited to share E3-substrate tagging by ubiquitin biotinylation (E-STUB) Nature Chemical Biology! E-STUB enables CUL-RING ligase substrate identification and may transform the way we study glues and PROTACs by directly studying substrate ubiquitylation. 1/
rdcu.be/dBZKx
Thrilled to share that we teamed up across National Cancer Institute and NIH NHLBI to discover #degraders against #hRpn13 that trigger #apoptosis in #cancer cells in a study led by Xiuxiu Lu with structural data from Monika chandravanshi. 🎉
link.springer.com/10.1038/s41467…
📢Deadline Extended📢
Researchers interested in #Ubiquitin function have until 01 April 2024 to submit for talk consideration at #Ubiq24 ! See the speaker line up below - all remaining slots will be filled by abstract submissions 🇵🇹
➡️bit.ly/3x4wl24 Vishva M. Dixit
Are you interested in strategies to control the spatial localization of your favorite protein at will? In our review, Saurav Kumar and I discuss the exciting development of chemical inducers of proximity to control subcellular protein localization. authors.elsevier.com/a/1ikNC3S7Zk9Z…
The momentum of our UBA5 research is a testament to the dedication and passion demonstrated by our research partners nationwide. We have made remarkable progress over the past two years, all thanks to them. ❤️❤️❤️
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