Excited to finally share our new findings! 'Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.” Rapoport Lab Harvard Medical School Harvard Med Cell Bio HHMI NEWS @sciencemagazine #cryoEM #proteinhomeostasis (1/n)
science.sciencemag.org/content/early/…
The Silvia Ramundo lab GMI Vienna has an open position in the Vienna BioCenter PhD Program Autumn call! More details: vbcphd.at
IMP Max Perutz Labs Vienna Universität Wien MedUni Wien IMBA
#OrganelleBiogenesis #ProteinHomeostasis #ChloroplastBiotechnology
Ummm this kind of runs counter to everything I’ve always thought of for Hsp70 and Hsp90 - very provocative in #proteinhomeostasis world… Molecular Cell cell.com/molecular-cell…
The Silvia Ramundo lab GMI Vienna has an open position in the Vienna BioCenter PhD Program Autumn call! More details: vbcphd.at
IMP Max Perutz Labs Vienna Universität Wien MedUni Wien IMBA
#OrganelleBiogenesis #ProteinHomeostasis #ChloroplastBiotechnology
Happy to announce that our protocol for measuring protein turnover rates has just been published in Nature Protocols (bit.ly/4nasiero) #Proteomics #ProteinMassSpectrometry #ProteinLifetime #ProteinTurnover #ProteinHomeostasis #Proteostasis Now looking for collaborators
#Review : The #epitranscriptome in #translationregulation →febs.onlinelibrary.wiley.com/doi/10.1002/18… #proteinsynthesis #RNA modifications #mRNAtranslation #proteinhomeostasis #RNA
📖 Make sure to check out this excellent guide to studying protein aggregation, included in issue 3:
🔗 buff.ly/40okiGN
✏️ By Joost Schymkowitz, Frederic Rousseau and colleagues VIB-KU Leuven Center for Brain & Disease Research KU Leuven
#proteinaggregation #fibrils #proteinhomeostasis #aggregationkinetics
The Silvia Ramundo lab GMI Vienna has an open position in the Vienna BioCenter PhD Program Autumn call! More details: training.vbc.ac.at/phd-program/
IMP Max Perutz Labs Vienna Universität Wien MedUni Wien IMBA
#OrganelleBiogenesis #ProteinHomeostasis #ChloroplastBiotechnology
Fruit flies adjust their diet when they need to eat more proteins thanks to proboscis gustatory receptor neurons medium.com/brains-and-beh… … #eLifedigest elifesciences.org/articles/31625 #proteinhomeostasis
This new #Review from Dr. Jawahar L. Mehta et al.
Targeting these #protein components of aggregates may be a promising therapeutic strategy for #cardiovascular pathologies associated with #aging , #ischemia , and/or #hypertension .
doi.org/10.20517/jca.2…
#Proteinhomeostasis
Signal sequences encode information for protein folding in the endoplasmic reticulum, say Sha Sun, Xia Li, and Malaiyalam Mariappan Mals Mariappan@Yale @yalewestcampus Yale Cell Biology: bit.ly/3ukxOfV
#ProteinHomeostasis #Biochemistry
Can treatment with Ficus deltoidea reduce lipid accumulation, improve redox status and protein homeostasis?
ftb.com.hr/current-issue/…
#nonfattyliverdisease #ubiquitinproteasomepathway #steatosis #proteinhomeostasis #ftbjournal #OpenAccess
The nuclear envelope surrounds and protects the genome. In JCellBiol, Mannino Philip Mannino and Lusk Patrick Lusk LusKing Lab explore the unique set of quality control pathways that maintain its identity and function. bit.ly/3wCFI5R
#Disease #Organelles #ProteinHomeostasis
Fluc-EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease, Sonja Blumenstock, Irina Dudanova et al, at @mpiNeuro, Max Planck Institute of Biochemistry (MPIB) et al, The EMBO Journal: @EMBOpress
embopress.org/doi/full/10.15…
#neurons #neuronal #proteostasis #proteinhomeostasis
Jierui Zhao, Mai Thu Bui, Juncai Ma, Byung-Ho Kang The Chinese University of Hong Kong - CUHK, Yasin Dagdas Yasin Dagdas GMI Vienna and colleagues show that CFS1 is an #autophagy adaptor that marks amphisomes -prevacuolar sorting hubs - in plants. bit.ly/3SfiA5x
#ProteinHomeostasis #PlantBiology
In addition to describe before, we have confirmed that #SSU -1 ablation restores #proteinhomeostasis in UNC-1 mutants. SSU-1 sulphates molecules to activates signalling pathways but this signal has to be desulphated by #sulfatases before joining a target. Rafa Vázquez 🍊 #SinCienciaNoHayFuturo
In search of a nuclear receptor candidate that explains the rescue, we look to #DAF -12 as a potential. However, we observed an opposite effect over #proteinhomeostasis and in turn, a #protective role of this pathway.
Rafa Vázquez 🍊 #SinCienciaNoHayFuturo IIS La Fe
Model for SS-guided protein folding in the ER. Sun, Li & Mals Mariappan@Yale @yalewestcampus Yale Cell Biology show that signal sequences encode information for protein folding in the endoplasmic reticulum. bit.ly/3ukxOfV
#ProteinHomeostasis #Biochemistry