Alex Bick
@AlexBickMDPhD
Genomic medicine physician-scientist @VUMCgenetics | via @harvardmed @mit_hst @MGHMedicine @broadinstitute. Disclosure: academic co-founder @tensixteenbio
ID:1147279621714432000
https://medsites.vumc.org/vanderbiltgeneticsinstitute/person/alexander-bick-md-phd 05-07-2019 23:02:32
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New work led by Mohammad Saadatagah Mohammadreza Naderian in JAMA Cardiology underscores that not all CHIP 🩸🧬 is the same. TET2 CHIP assoc'd w/ ⬆️ IL-6 and AF risk, esp when clones are large.
jamanetwork.com/journals/jamac…
Art Schuermans Alex Bick Pradeep Natarajan Iftikhar J. Kullo Christie Ballantyne
Life insurers have clearly recognized the value of genetics in lifetime risk prediction. But need policies in place so life insurance premiums remain unaffected & can truly be utilized for health promotion via Eric Topol
Would you believe me if I told you that a single variant in a non-coding RNA explains ~0.5% of all undiagnosed individuals with neurodevelopmental disorders (NDD) in Genomics England ???
I didn’t initially either, but here is the story of RNU4-2 🧵1/9
Thrilled to receive an NIH NHLBI K23 Award to study CAV after heart transplantation using multiomics approaches! Couldn’t have done it without amazing mentorship! #RaviShah Jane Freedman MD Kelly Schlendorf Jeff Rathmell Nathan Tucker Javid Moslehi #YuShyr
Fantastic news paper by Lars Velten characterizing single cell epimutations via Mission Bio Tapestri as lineage markers in the hematopoietic system.
biorxiv.org/content/10.110…
Thanks Alex for live-illustrating our #singlecellgenomicsday workshop today! You can access the free Youtube livestream at satijalab.org/scgd/
Very excited to share our review on genetic variation across and within individuals led by Zhi Yu Tim Coorens! nature.com/articles/s4157… Nature Reviews Genetics
BIG NEWS: The AllofUsResearch Program has surpassed 10K registered researchers! 🎉 I’m thrilled that we’ve reached this milestone 2.5 years ahead of schedule. Thank you to everyone who has worked so hard to grow our researcher cohort. (1/2)
Why do Latino children have the highest risk for childhood leukemia in the US? We identify one cause for this in a paper out in Cell Genomics today, led by Adam de Smith, Lara Wahlster, Soyoung Elizabeth Jeon, Fulong Yu, Charleston Chiang, & colleagues:
cell.com/cell-genomics/…
CHIP: The Silent Threat Steps Into the Limelight - what clinicians should know about CHIP and risk score developed by Lachelle Dawn for cancer and predicts CV Mohammad Saadatagah Pradeep Natarajan Alex Bick medscape.com/viewarticle/ch…
New manuscript from our labs, collaboration with Alex Bick lab led by Brett Heimlich Pawan Bhat Alyssa Parker checkout the tweetorial 👇!
Excited to share this paper in Blood Advances led by Brett Heimlich, Pawan Bhat & Alyssa Parker with Ferrell Lab that uses mitochondrial lineage tracing techniques pioneered by Peter van Galen Caleb Lareau, Vijay Sankaran to identify transcriptional consequences of #CHIP