I want to show you what microhemorrhages and brain swelling from anti-amyloid immunotherapies look like under a microscope. In this severe case, many of the vessels simply disintegrated - see the bleeding and numerous aneurysms in this striking image. #Alzheimer #lecanemab
Alright, ready for some controversy #LongCovid community? I'm not suggesting anyone take up smoking as this study suggests activating this a7 Nicotinic receptor can create more ACE2 receptors, however, it goes to show that the spike doesn't only bind to the ACE2 receptor. (1/10)
This time, a brain with amyloid peptide, one of the misfolded proteins accumulating in #Alzheimer 's Disease. Note the intense inflammatory response in the hippocampus. #fluorescencemicroscopy
Please retweet! We are hiring an institutional postdoctoral fellow who will jointly work with three PIs! Join our young & energetic labs to work at the interface of biology & engineering!! Check Indian Institute of Technology Jodhpur website
Biopatrika Voices of Indian Academia
📌Cerebral Amyloid Angiopathy Diagnosis
🩸🧠Superficial bleeding combinations enough to diagnose probable CAA within the Boston Criteria v2.0 (in the absence of microbleeds or ICH)
#MedTwitter #MedStudentTwitter #MedEd #FOAMed
#neurotwitter #Neurology #stroke #Neurosurgery …
Knight ADRC Washington University Department of Neurology 18F-flortaucipir PET visual interpretation was found to be moderately consistent with CSF p-tau181 (n = 124/144, 86.1%, κ= 0.526). Most discordant cases (n = 18/20) are amyloid-positive and CSF p-tau181 positive, but tau-negative on visual interpretation (8/n)
Congrats to Chanung Wang and David Holtzman on a really exciting and impressive paper on sleep, ApoE, amyloid, and tau. Center On Biological Rhythms And Sleep
Stew Peters Here is some data that makes a connection between these venom toxic-like peptides and not only the formation of fibrin amyloid microclots found in covid and vaccine patients but also the mechanism that prevents their breakdown.
twitter.com/Minecraft4n00b…
Human islet amyloid polypeptide (IAPP) aggregates contribute to the pathogenesis of painful diabetic neuropathy
On Neurodiab website a signaling of articles on #diabeticneuropathy
The 73rd NEUROdiab Publication News is by Anna Körei (neurodiab.eu/publication-ne…)
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Wow! 3 cardiac #amyloid patients treated with polyclonal IgG #antibodies to human #ATTR . After 3 years, there was nearly complete reversal of disease! Read here 'Reversal of ATTR Amyloidosis–Related Cardiomyopathy' nejm.org/doi/full/10.10… #cardiotwitter #echofirst #HFpEF
Slowly growing lung mass FNA: Amorphous deposits similar in appearance to colloid. Dx: 'amyloid tumor'. Characteristic 🍏 green on Congo red stain. #pathTwitter #pathResidents #cytology #cytopath #pulmpath
Dr G Rajesh (Gopalan Nair Rajesh) This was our amyloid case sir..50/M,came ATTR positive on genetic study,Tc99 PYP positive,fat pad biopsy +ve,we got free tafamidis for 4 months under compassionate use programme for him FREE with DCGI approval frm USA last year.Patient’s elder cousin is also ATTR positiv CM.
Lon S. Schneider, MD Nicolas Villain LogarithmicDis Reshma Ramachandran David Rind Sarah Ackley, PhD Gregg Gonsalves Ash Paul Jennifer Richards philip robinson 🍊 Robert Howard Seb Walsh Jason Cohen Jamie Timmons Ryan Townley Joseph Therriault Timothy Daly, PhD Nick Corriveau-Lecavalier, PhD Trey Bateman David Jones Chuck Gartland Erick Turner kate foley, phd Alberto J Espay Stefano L. Sensi Vincent Planche Prof Scott Ayton Karl Herrup Giovanni Frisoni Matteo Cesari George Perry Sam Gandy MD PhD Gill Livingston Kariem Ezzat Andrea Sturchio Samir EL Andaloussi Roxanne Khamsi Richard Merrick Matthew Schrag Kathy Liu Naomi Kresge Gerry Scheetz Alette Wessels Former Account of Eli Lilly and Company Matthew Herper Adam Feuerstein Amsterdam UMC Journal of Alzheimer's Disease jpreventionalzheimer U.S. FDA Going out on a limb here, but if ARIA helped improve cognition in the RCTs, I think we would have had detailed and full reporting of these results including a catchy acronym. Amyloid Related Iatrogenic Amelioration of Cognitive Decline (ARIA-CD)
